The simplest definition of multiple myelomas is that they are a form of a cancer, which arises from a single blood cell in the bone marrow, called the plasma cells. The plasma cells that become cancerous are termed myeloma cells. Myelomas do not represent a single disease entity, but rather encompass a large number of subtypes with diverse natural histories, from those that remain indolent for long periods to those that grow rapidly, and can prove fatal very quickly if untreated.

Types

There are four subtypes of multiple myeloma (typically referred to as simply myeloma or plasma cell myeloma; also known as myelomatosis), dependent on the type of monoclonal protein produced. Each type appears to be associated with a different disease pattern; for example, IgA myeloma is associated with more organ damage, such as in the kidneys, than bone disease. About 50 per cent of patients with myeloma have cytogenetic abnormalities. The bone marrow often contains in excess of 30 per cent plasma cells. Rarely a variant of myeloma, called smoldering myeloma is diagnosed when the plasma cells in the bone marrow are between 10 and 30 per cent and no other findings of myeloma are present.

Why you should choose Treatment of Multiple Myelomas Cancer at World Class Cancer Hospital in India

Globally Trained & Highly Experienced Myelomas Cancer Specialists – Benefit from the expertise of Myelomas Cancer Specialists who have worked at World’s leading Myelomas Cancer Treatment hospitals for decades and follow most advanced cancer treatment protocols.

World’s Lowest Cost Cancer Treatment Packages. Best quality Drugs, Medicines and Consumables for Myelomas Cancer Care are produced in India at lowest cost and exported all over the world.

Complete Cancer Care with latest High-end technology infrastructure like Robotic Surgery System, Brain Suite, Novalis Radiosurgery TX, PET Scan, CyberKnife , Gamma Knife, IMRT and IGRT that help quick diagnosis and recovery.

Well trained English speaking Doctors, Nurses and Support Staff provide competent and compassionate Cancer care.

Stem Cell Transplant for Multiple Myeloma

A stem cell transplant, also called a bone marrow transplant, can be an effective part of treatment for multiple myeloma. Hematopoietic stem cells reside in the bone marrow. They can produce all types of blood cells, including white blood cells, red blood cells, and platelets. In this procedure, hematopoietic stem cells are collected from the patient or another person.

Autologous Transplantation

A patient’s own stem cells are collected before chemotherapy, then returned when chemotherapy is complete.

Allogeneic Transplantation

Stem cells are given by a donor, most commonly a brother or sister. Autologous stem cell transplantation is more common for multiple myeloma, but either type of transplant can be used.

CAR T-cell Therapy for Multiple Myeloma

Chimeric antigen receptor (CAR) T-cell therapy is a type of cancer immunotherapy. It helps the body’s own immune system find and attack cancer cells. CAR T-cell therapy is also sometimes talked about as a type of cell-based gene therapy, because it involves altering the genes inside certain immune cells to help them attack the cancer.

To make this treatment, immune cells called T cells are taken from the person’s blood during a process called leukapheresis. Blood is removed through an IV line and goes into a machine that takes out the T cells. The remaining blood then goes back into the body. This process typically takes a few hours, and it might need to be repeated.

The T cells are then frozen and sent to a lab, where they are genetically altered so they have specific receptors (called chimeric antigen receptors, or CARs) on their surface. These receptors help the T cells attach to proteins on cancer cells. The T cells are then multiplied in the lab, which typically takes several weeks.

Once the CAR T cells are ready, the patient gets chemotherapy for a few days to help prepare the body. Then the CAR T cells are infused back into the patient’s blood, where they can seek out the cancer cells and help the immune system attack them.

Specialists will have a structured management plan for patients with symptomatic myeloma comprising specific supportive care to control symptoms, and also to minimise the risks of myelomarelated complications, such as bone disease and kidney failure, in addition to specific anti-myeloma therapy. Since the disease remains incurable at present, most specialists tend to offer treatment only to patients who become symptomatic.

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Patient Experience – Ms. Lusungu from Zambia came to India for Successful Cancer Treatment

“I can’t begin to tell you how much I appreciate everything you and all of your coworkers have done for use. To know that someone would be there to meet us at the end of our long trip and we didn’t have to worry about anything. We got to the hospital late and were taken directly to our rooms to rest. From that moment on we were treated like God.

The hospital was so clean, everyone always smiles, and your not just a number. The professionalism was out of this world. When we left We all agreed that if we ever had to do this again, we would be back in a heartbeat! Leaving the Hospital pulled at our heartstrings because the nurses and doctors became our friends! ”