What is Advanced Nuclear Medicine Therapy ?
Nuclear Medicine Therapy is an innovative and transformative approach in the relentless battle against cancer, offering newfound hope to those who have exhausted traditional treatment options such as chemotherapy and surgery. This cutting-edge therapy has demonstrated its ability to effectively control symptoms and stabilize tumours, proving to be a ray of light for patients facing metastatic Prostate Cancer, Neuro Endocrine Tumours, and Hepatocellular Carcinoma when all other avenues have been explored.
What are the unique benefits of Nuclear Medicine Therapy Treatments?
a) Targeted Tumour Destruction – At the core of Nuclear Medicine Therapy’s efficacy lies the utilization of radioactive molecules as targeted drugs, known as molecular radiotherapy. These specialized drugs possess a remarkable ability to recognize and bind to tumour cells with precision. Following intravenous administration, they circulate throughout the body, seeking out their designated targets, and delivering radiation directly to the malignant cells, ultimately leading to their demise.
b) Protecting Healthy Cells – The intricacy of this therapeutic approach lies in its ability to distinguish between healthy and cancerous cells, sparing normal tissues from undue harm. Witnessing the careful orchestration of these radioactive agents as they adhere to and destroy tumour cells is both remarkable and promising.
c) Safer Outcomes – Even though the majority of the drug fulfils its intended purpose, some fractions remain unbound to cancerous cells, circulating in the bloodstream until naturally eliminated, predominantly through urine excretion.
Nuclear Medicine Therapy stands as a testament to the advancements in medical science, embodying the culmination of years of research and dedication to finding more effective cancer treatments. It is an earnest endeavour to confront this formidable disease and alleviate the suffering of patients for whom conventional therapies have fallen short.
As we continue to explore the potential of Nuclear Medicine Therapy, we embrace a new era in cancer care, built upon the principles of precision medicine and targeted therapies. With its profound impact on controlling cancer progression and improving patients’ quality of life, this innovative approach heralds a promising future in the on-going fight against cancer.
Why you should choose World Class Hospitals in India for Most Advanced Nuclear Medicine Therapy ?
Most Advanced Nuclear Medicine Therapies available at Most Affordable Cost at World Class Hospitals in India
1) PSMA Therapy for Metastatic Prostate Cancer
Targeted Alpha Therapy (TAT) or Alpha PSMA Therapy using radiolabeled PSMA inhibitors, has brought about a massive leap for treatment of metastatic castration resistant prostate cancer (mCRPCa) patients.
Prostate-specific membrane antigen (PSMA) is a protein found in small amounts in the prostate gland. When a patient has prostate cancer, he has many times more PSMA than normal. This makes PSMA a good target for treating advanced prostate cancer. You might hear this new treatment called lutetium PSMA therapy, Lu-PSMA, or just PSMA therapy.
PSMA therapy uses two drugs joined together. One is a molecule called PSMA-617. It finds and attaches to PSMA on cancer cells. The other is a radioactive medicine named lutetium 177 (Lu 177). It binds to PSMA617, which carries it into the tumour.
This helps destroy cancer with less harm to healthy tissue. PSMA therapy won’t cure prostate cancer, but it may ease symptoms, slow its growth, and help you live longer.
PSMA therapy is for men with metastasized prostate cancer who’ve tried hormone treatments and chemotherapy. When they don’t slow cancer spread, PSMA therapy may be an option.
The FDA-approved drug, called Pluvicto (lutetium Lu 177 vipivotide tetraxetan), is a new radiation pharmaceutical that is administered through injection or infusion. The drug travels throughout the body and targets cancer cells with the PSMA biomarker, a protein found on most prostate cancer cells In most cases Prostate Cancer patients treated with PSMA therapy, Lu-PSMA, or just PSMA therapy resulted in good outcomes. The patients PSA levels dropped significantly and the PSMA PET CT scan done for treatment response assessment demonstrated a good partial response with a significant reduction in PSMA uptake in most of the lesions. The patient that shoulder and hip pains are significantly reduced. The patient has no complaints of dry mouth or any other side effects. His appetite and overall general condition have improved
Is PSMA approved for prostate cancer?
On March 23, 2022, the FDA approved Pluvicto (lutetium Lu 177 vipivotide tetraxetan, also known as 177Lu-PSMA-617) for the treatment of adult patients with prostate-specific membrane antigen (PSMA)- positive metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor pathway
2) PRRT Nuclear Therapy for Neuroendocrine Tumours / Hepatocellular Carcinoma
A PRRT treatment also known as peptide receptor radionuclide therapy treatment targets tumours of some types. A tiny but powerful dose of radioactivity destroys tumor cells by binding to their receptors. The treatment does not cure tumours, but it can slow or stop their growth. PRRT is a treatment option that is highly effective in controlling advanced, metastatic or inoperable, progressive neuroendocrine tumors. PRRT is rarely curative but has been shown to help relieve symptoms, shrink tumours, and slow the progression of the disease. PRRT is actually administering a radioisotope which targets the somatostatin receptors which are expressed on these patients of well-differentiated neuroendocrine tumours and by actually targeting these somatosatin receptors we are able to deliver a very high dose of radioisotopes which goes and attaches to the tumour cells without damaging the surrounding cells.
This becomes very important because many patients with neuroendocrine tumours have got large volume metastatic disease in the liver we need Isotopes which will go and Target the tumor without damaging the normal liver or in patients who’ve got skeletal metastasis.
Isotopes go and target the tumour without damaging the surrounding bone marrow and by using PRRT we are able to do exactly this and that is the reason why PRRT is often called the Magic Bullet therapy because it’s goes and attaches these radio peptides they go and attach directly to the tumour cells without actually causing any kind of harm to the surrounding structures. PRRT can now be done with various beta emitting radioisotope which has got a higher energy than loticium and can be used to Target bigger tumours or patients who got larger metastatic disease
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