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Haematopoietic stem cell transplantation (HSCT) treatment helps to slow the progression of Scleroderma ?

World’s Most Advanced and Affordable HSCT Treatment for Scleroderma / Systemic Sclerosis at World Class Hospitals In India

Scleroderma, Systemic Sclerosis patients from Europe, America have already been treated successfully at World Class HSCT Hospital in India.

What is Scleroderma and how does HSCT Treatment help ?

Scleroderma is a chronic autoimmune disorder in which antibodies destroy the communication between nerves and muscle, resulting in weakness of the skeletal muscles. Scleroderma makes the body produce too much collagen, a protein that is required for healthy skin and tissue.

Scleroderma affects the voluntary muscles of the body, especially those that control the eyes, mouth, throat and limbs. People with Scleroderma have muscle weakness that worsens throughout the day. This autoimmune disease affects the neuromuscular system.

It’s an autoimmune condition, which means the immune system attacks the body instead of protecting it.

Scleroderma isn’t contagious or infectious, meaning you can’t get it from other people.

Types of scleroderma :

Localized Scleroderma : Localized means concentrated in one area. Localized scleroderma only affects one part of the body (usually the skin). It causes thick patches or streaks on the skin that feel waxy. Localized scleroderma can get better (resolve) on its own. It usually doesn’t spread to other parts of the body.

Systemic Sclerosis : Systemic sclerosis can affect other organs, in addition to the skin. It can affect parts of respiratory system (the organs that help breathe and smell) and the digestive system (the organs that help you turn foods and drinks into energy). Scleroderma is more likely to cause serious complications if it affects the patients ability to breathe or process nutrition.

Symptoms of Scleroderma :

The symptoms can affect many parts of the body like :-
  • Hardened or thickened skin that looks shiny and smooth. It’s most common on the hands and face.
  • Ulcers or sores on the fingertips
  • Small red spots on the face and chest
  • Firm, oval-shaped patches on the skin
  • Trouble swallowing
  • Painful or swollen joints
  • Muscle weakness Swelling, mostly of the hands and fingers (edema)
  • Shortness of breath
  • Belly cramps and bloating, Heartburn
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Treatment options for Scleroderma

There is no treatment that can cure or stop the overproduction of collagen that is characteristic of scleroderma. Getting pain relief through nonsteroidal, anti-inflammatory medications or corticosteroids · Easing skin itchiness with skin lotions etc. Convention treatment that suppress the immune system, such as those taken after organ transplants, may help reduce progression of some scleroderma symptoms, such as the thickening of the skin or worsening of lung damage. Hematopoietic Stem Cell Transplantation (HSCT) has however emerged as a promising treatment option for Scleroderma

How does HSCT help for patients with Myasthenia Gravis?

HSCT is a type of bone marrow transplant that involves removing hematopoietic stem cells (HSCs) from the bone marrow and transplanting them back into the patient after administering high-dose chemotherapy. HSCs are the cells responsible for producing all the different types of blood cells in the body, including red blood cells, white blood cells, and platelets.

The goal of HSCT in Scleroderma is to “reset” the immune system by removing the damaged immune cells and replacing them with healthy ones. This can help to stop the autoimmune attack on the nerves and halt the progression of the disease.

How does HSCT for Scleroderma work ?

In a typical HSCT procedure for Scleroderma, the patient undergoes a series of tests to determine their eligibility for the treatment. This includes a complete medical evaluation, imaging studies, and a series of blood tests to determine the patient’s overall health and to identify any underlying health conditions that may affect the success of the procedure.

Once the patient is deemed eligible for HSCT, they undergo a period of high-dose chemotherapy to prepare for the transplant. This involves administering high doses of chemotherapy drugs to destroy the patient’s existing immune cells. After the chemotherapy is complete, the HSCs are removed from the bone marrow and are then reinfused back into the patient.

The recovery period following HSCT is 2- 3 weeks and the patient may need to remain in the hospital for 30 days. During this time, the patient will be closely monitored for any signs of infection or other complications, and they will receive supportive care to help them through the recovery process.

How does HSCT benefit Scleroderma

One of the key benefits of HSCT for Scleroderma is that it can provide long-term relief from the symptoms of the disease. In many cases, patients who undergo HSCT experience significant improvement in their symptoms, and they may even experience complete remission of the disease.

HSCT is now considered a promising treatment option for Sclerodermaand it is being used with increasing frequency to treat patients with this condition. If you or a loved one is living with Scleroderma contact Helpdesk for an expert opinion from top specialists at our world class hospitals in India

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Patient Testimonials – What People Say about us

More than 1000 International Patients have benefited from HSCT in India.

Marjorie from Australia

“I was obviously quite nervous but my confidence was high and I convinced myself that I had made the right decision. I am now 1 year post transplant, and I now know that I did make the right decision.

Immediately on arriving in India, many tests were done on my whole body and, once the medical team were wholly satisfied with my strength and physicals, on 1 August 2017, I went through the actual HSCT procedure. The medical team visited me daily and insisted that they were there to help me and I wasn’t to unduly worry about this treatment. I didn’t, and I was placed on a special diet to maintain my strength. My son was given a uniform to wear to avoid any infections and I was monitored several times a day to check on my health.

Without a doubt, I am happy that I had the transplant and that I had it done by hsct specialist, Artemis Hospital, New Delhi. If anyone is thinking of doing HSCT, it is important that you do your research and are happy with your decision. I have no regrets, my EDSS was 6.5 before transplant and although it has only improved slightly, I am able to walk without any aid other than my stick, which I was not able to do before HSCT. I make sure I do exercise each and every day and I am overall happy with my recovery thus far.”

Linda from Netherlands

“Linda discovered that she had the disease in 2007, when she was 24. She went to the doctor because she sometimes saw double. Two years ago, her health deteriorated rapidly. The supermarket 100 meters away was too far to walk .Linda came to India with her friend Leone as her attendant who is also delighted with hospitality and comfortable facilities at Triple Hepa Deluxe room where both of them stayed for 30 days at World class Hospital in India.

My living room is my living space, I’m quarantined there. But that’s okay, I feel so incredibly good,” says Linda. On April 2, she got her stem cells back. “I see that as my birthday. The treatment has been intense, especially the chemotherapy. “Luckily my best friend Leoni was there.

She was my support and rock and could sense what I needed. It was a safe feeling that she was there. Now my left leg can go straight ahead again. “No swing or other tricks to get him forward. “

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