Bladder cancer is a type of malignancy arising from the epithelial lining (i.e., the urothelium) of the urinary bladder. It is a disease in which abnormal cells multiply without control in the bladder. The most common type of bladder cancer recapitulates the normal histology of the urothelium and is known as transitional cell carcinoma or more properly urothelial cell carcinoma.
Primary radiation therapy generally involves a radiation dose of 6,000 to 7,000 rad to the bladder in patients not fit or not willing to undergo surgery.
Chemotherapy used to treat bladder cancer can be either local or systemic.
Bacillus Calmette-Guerin (BCG) is the most commonly prescribed immunotherapeutic agent for use in bladder cancer treatment to prevent recurrences in superficial bladder cancer.
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